Target Selective Drug Delivery Peptide Capable of Crossing the Blood Brain Barrier

Technology Summary

Dr. Maegan Weltzin has engineered a target selective dual drug delivery system that is able to deliver cargo into the brain by a single intravenous injection. The peptide has potential to enhance treatment for neurological disorders and to alleviate depressive symptoms without the drawbacks of traditional antidepressants, offering a potentially faster-acting and more effective treatment option.


Background

In light of the current opioid use epidemic, research in the area of alternative pain therapies is extremely important. Peptides with increased selectivity that can deliver cargo and penetrate the blood brain barrier are thus needed.

Description

This innovation utilizes an engineered peptide capable of transporting therapeutic cargo directly across the blood brain barrier via a single intravenous injection. By combining target selectivity with efficient transport mechanisms, the dual drug delivery system addresses critical challenges in treating central nervous system conditions.

Applications

  • Pharmaceuticals: Drug delivery systems for crossing the blood brain barrier.
  • Therapeutics: Potential treatment for inflammation, chronic pain, and depression.
  • Prospective Impact: Enhance treatment potential for neurological disorders.

Advantages

  • Target Selective: Delivers therapeutics directly to target sites.
  • Cargo Transport: Capable of transporting drug payloads across tissue barriers.
  • Blood Brain Barrier Penetration: Crosses the blood brain barrier via a single intravenous injection.

Intellectual Property

  • US Patent Application No. 18/422,865

Key Words

Target selective drug delivery, Peptide, Blood brain barrier, Intravenous injection, Neurological disorders, Chronic pain, Depression, Alternative pain therapy, Maegan Weltzin

Innovator(s)

Dr. Maegan Weltzin

Opportunity

Available to license

Contact Licensing Officer